PRRX1 Rabbit Polyclonal Antibody

CAT#: TA349182

Rabbit Polyclonal Anti-MEK1/2 Antibody

Product Images

Western blot analysis of MEK1/2 in human brain tissue lysate with MEK1/2 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1 - 2 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: MEK1/2 antibody was raised against a 15 amino acid peptide near the center of human MEK1.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: MEK1/2 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 43 kDa; Observed: 44 kDa
• Gene Name: paired related homeobox 1
• Database Link:
  NP_073207
  Entrez Gene 18933 MouseEntrez Gene 266813 RatEntrez Gene 5396 Human
  UniProt ID P54821
• Background: The mitogen-activated protein kinase kinase 1 (MAP2K1, also known as MEK1) and the highly homologous MEK2 are members of the dual specificity protein kinase family (1). MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals (2). MEK1 lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, MEK1 is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development (2).
• Synonyms: AGOTC; PHOX1; PMX1; PRX-1; PRX1

Reference Data

• Protein Families: Transcription Factors