TRPC3 Rabbit Polyclonal Antibody

CAT#: TA349194

Rabbit Polyclonal Anti-TRPC3 Antibody


USD 484.00

5 Days*

Size
    • 100 ug

Product Images

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Specifications

Product Data
Applications WB
Recommended Dilution WB: 1 - 2 ug/mL
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen TRPC3 antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human TRPC3.
Formulation PBS containing 0.02% sodium azide.
Concentration 1 mg/ml
Purification TRPC3 Antibody is affinity chromatography purified via peptide column.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size Predicted: 90, 93, 101 kDa; Observed: 93 kDa
Gene Name transient receptor potential cation channel subfamily C member 3
Background The mammalian transient receptor potential (TRP) superfamily can be divided into three major families including the "canonical TRP" (TRPC) family. The seven members of this family share the activation through PLC-coupled receptors and have been suggested to be components of receptor-regulated cation channels in different cell types. Furthermore, the members of the TRPC3/6/7 subfamily can be activated by diacylglycerol analogs, suggesting a possible mechanism of activation of these channels by PLC-coupled receptors. TRPC3 encodes a Ca2+-permeant channel that is agonist-activated but not store-operated or directly receptor-activated. TRPC3 physically interacts with TRPC6 and TRPC7 and forms functional tetrameric channels.
Synonyms SCA41; TRP3
Reference Data
Protein Families Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane

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