Retinoic Acid Receptor beta (RARB) Rabbit Polyclonal Antibody

CAT#: TA349211

Rabbit Polyclonal Anti-RARB Antibody

Product Images

Gel: 10%SDS-PAGE Lysate: 40 μg Lane 1-2: K562 cells human normal liver tissue Primary antibody: TA349211 (RARB Antibody) at dilution 1/283 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 20 seconds

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 200-1000
  WB positive control: K562 cells and human normal liver tissue
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human RARB
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 50 kDa
• Gene Name: retinoic acid receptor beta
• Database Link:
  NP_057236
  Entrez Gene 218772 MouseEntrez Gene 5915 Human
  UniProt ID P10826
• Background: This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. The gene expresses at least two transcript variants; one additional transcript has been described, but its full length nature has not been determined
• Synonyms: HAP; MCOPS12; NR1B2; RARbeta1; RRB2

Reference Data

• Protein Families: Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
• Protein Pathways: Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer