DKK3 Rabbit Polyclonal Antibody

CAT#: TA349296

Rabbit Polyclonal Anti-DKK3 Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane: Human fetal brain tissue Primary antibody: TA349296 (DKK3 Antibody) at dilution 1/200 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 40 seconds

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA349296 (DKK3 Antibody) at dilution 1/50 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA349296 (DKK3 Antibody) at dilution 1/50, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human brain tissue using TA349296 (DKK3 Antibody) at dilution 1/50 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human brain tissue using TA349296 (DKK3 Antibody) at dilution 1/50, treated with fusion protein. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Human fetal brain tissue
  IHC: 50-200
  Positive control: Human thyroid cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human DKK3
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 38 kDa
• Gene Name: dickkopf WNT signaling pathway inhibitor 3
• Database Link:
  NP_056965
  Entrez Gene 50781 MouseEntrez Gene 27122 Human
  UniProt ID Q9UBP4
• Background: This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein.
• Synonyms: REIC; RIG

Reference Data

• Protein Families: Druggable Genome, Secreted Protein