E2F6 Rabbit Polyclonal Antibody

CAT#: TA349302

Rabbit Polyclonal Anti-E2F6 Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane 1-5: LoVo cells A549 cells human hepatocellular carcinoma tissue Jurkat cells Hela cells Primary antibody: TA349302 (E2F6 Antibody) at dilution 1/650 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 30 seconds

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  Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA349302 (E2F6 Antibody) at dilution 1/60 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA349302 (E2F6 Antibody) at dilution 1/60, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TA349302 (E2F6 Antibody) at dilution 1/60 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TA349302 (E2F6 Antibody) at dilution 1/60, treated with fusion protein. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: LoVo and A549 cells, human hepatocellsular carcinoma tissue, Jurkat and Hela cells
  IHC: 100-300
  Positive control: Human cervical cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human E2F6
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 32 kDa
• Gene Name: E2F transcription factor 6
• Database Link:
  NP_937987
  Entrez Gene 50496 MouseEntrez Gene 1876 Human
  UniProt ID O75461
• Background: This gene encodes a member of a family of transcription factors that play a crucial role in the control of the cell cycle. The protein encoded by this gene lacks the transactivation and tumor suppressor protein association domains found in other family members, and contains a modular suppression domain that functions in the inhibition of transcription. It interacts in a complex with chromatin modifying factors. There are pseudogenes for this gene on chromosomes 22 and X. Alternative splicing results in multiple transcript variants.
• Synonyms: E2F-6

Reference Data

• Protein Families: Transcription Factors