DUSP19 Rabbit Polyclonal Antibody

CAT#: TA349309

Rabbit Polyclonal Anti-DUSP19 Antibody

Product Images

Gel: 15%SDS-PAGE, Lysate: 40 ug, Lane: Mouse liver tissue, Primary antibody: (DUSP19 Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds

• 

  The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using (DUSP19 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)

• 

  The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using (DUSP19 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 2000-5000, WB: 500-2000, IHC: 50-200
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human DUSP19
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 24 kDa
• Gene Name: dual specificity phosphatase 19
• Database Link:
  NP_543152
  Entrez Gene 68082 MouseEntrez Gene 142679 Human
  UniProt ID Q8WTR2
• Background: Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP19 contains a variation of the consensus DUSP C-terminal catalytic domain, with the last serine residue replaced by alanine, and lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs.
• Synonyms: DUSP17; LMWDSP3; SKRP1; TS-DSP1

Reference Data

• Protein Families: Druggable Genome, Phosphatase