Lamin B1 (LMNB1) Rabbit Polyclonal Antibody

CAT#: TA349381

Rabbit Polyclonal Anti-LMNB1 Antibody

Product Images

Gel: 6%SDS-PAGE Lysate: 40 μg Lane 1-7: Hela cells HT29 cells human fetal liver tissue Human testis tissue 231 cells K562 cells human bladder transitional cell carcinoma tissue Primary antibody: TA349381 (LMNB1 Antibody) at dilution 1/750 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 second

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  Immunohistochemistry of paraffin-embedded Human tonsil tissue using TA349381 (LMNB1 Antibody) at dilution 1/60 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human tonsil tissue using TA349381 (LMNB1 Antibody) at dilution 1/60, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA349381 (LMNB1 Antibody) at dilution 1/60 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA349381 (LMNB1 Antibody) at dilution 1/60, treated with fusion protein. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1000-5000
  WB positive control: Hela and HT-29 cells, human fetal liver and testis tissue, 231 and K562 cells, human bladder transitional cells carcinoma tissue
  IHC: 100-300
  Positive control: Human tonsil
  Predicted cell location: Nucleus and Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human LMNB1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 67 kDa
• Gene Name: lamin B1
• Database Link:
  NP_005564
  Entrez Gene 16906 MouseEntrez Gene 116685 RatEntrez Gene 4001 Human
  UniProt ID P20700
• Background: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD).
• Synonyms: ADLD; LMN; LMN2; LMNB