MAD2L1 binding protein (MAD2L1BP) Rabbit Polyclonal Antibody

CAT#: TA349386

Rabbit Polyclonal Anti-MAD2L1BP Antibody

Product Images

Gel: 10%SDS-PAGE Lysate: 40 μg Lane 1-4: A549 cells 231 cells PC3 cells hela cells Primary antibody: TA349386 (MAD2L1BP Antibody) at dilution 1/675 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 20 seconds

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  Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA349386 (MAD2L1BP Antibody) at dilution 1/65 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA349386 (MAD2L1BP Antibody) at dilution 1/65, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using TA349386 (MAD2L1BP Antibody) at dilution 1/65 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using TA349386 (MAD2L1BP Antibody) at dilution 1/65, treated with fusion protein. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: A549, 231, PC3 and hela cells
  IHC: 50-200
  Positive control: Human cervical cancer
  Predicted cell location: Cytoplasm or Nucleus
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human MAD2L1BP
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 31 kDa
• Gene Name: MAD2L1 binding protein
• Database Link:
  NP_001003690
  Entrez Gene 9587 Human
  UniProt ID Q15013
• Background: The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
• Synonyms: CMT2

Reference Data

• Protein Families: Druggable Genome