MCM5 Rabbit Polyclonal Antibody

CAT#: TA349392

Rabbit Polyclonal Anti-MCM5 Antibody

Product Images

Gel: 6%SDS-PAGE Lysate: 40 μg Lane 1-5: HepG2 cells K562 cells Jurkat cells 231 cells hela cells Primary antibody: TA349392 (MCM5 Antibody) at dilution 1/475 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 30 seconds

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  Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using TA349392 (MCM5 Antibody) at dilution 1/40 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using TA349392 (MCM5 Antibody) at dilution 1/40, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA349392 (MCM5 Antibody) at dilution 1/40 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA349392 (MCM5 Antibody) at dilution 1/40, treated with fusion protein. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: HepG2, K562, Jurkat, 231 and hela cells
  IHC: 50-200
  Positive control: Human gasrtic cancer
  Predicted cell location: Nucleus
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human MCM5
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 82 kDa
• Gene Name: minichromosome maintenance complex component 5
• Database Link:
  NP_006730
  Entrez Gene 17218 MouseEntrez Gene 4174 Human
  UniProt ID P33992
• Background: The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.
• Synonyms: CDC46; P1-CDC46

Reference Data

• Protein Families: Stem cell - Pluripotency, Transcription Factors
• Protein Pathways: Cell cycle, DNA replication