Apc2 (ANAPC2) Rabbit Polyclonal Antibody

CAT#: TA349476

Rabbit Polyclonal Anti-ANAPC2 Antibody


USD 345.00

In Stock*

Size
    • 100 ul

Product Images

Other products for "ANAPC2"

Specifications

Product Data
Applications IHC, WB
Recommended Dilution WB: 200-1000
WB positive control: Hela, Jurkat and NIH/3T3 cells
IHC: 25-100
Positive control: Human colon cancer
Predicted cell location: Cytoplasm
Reactivities Human, Mouse
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein of human ANAPC2
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 94 kDa
Gene Name anaphase promoting complex subunit 2
Background A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation.
Synonyms APC2
Reference Data
Protein Families Druggable Genome
Protein Pathways Cell cycle, Oocyte meiosis, Progesterone-mediated oocyte maturation, Ubiquitin mediated proteolysis

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.