APPBP1 (NAE1) Rabbit Polyclonal Antibody
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Other products for "NAE1"
Specifications
Product Data | |
Applications | ELISA, IHC |
Recommended Dilution | IHC: 15-50 Positive control: Human cervical cancer Predicted cell location: Nucleus |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Fusion protein of human NAE1 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | NEDD8 activating enzyme E1 subunit 1 |
Database Link | |
Background | The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene. |
Synonyms | A-116A10.1; APPBP1; HPP1; ula-1 |
Reference Data | |
Protein Pathways | Alzheimer's disease |
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