Aprataxin (APTX) Rabbit Polyclonal Antibody

CAT#: TA349494

Rabbit Polyclonal Anti-APTX Antibody

Specifications

Product Data

• Applications: ELISA, IHC
• Recommended Dilution: IHC: 50-200
  Positive control: Human thyroid cancer
  Predicted cell location: Nucleus
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human APTX
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: aprataxin
• Database Link:
  NP_778239
  Entrez Gene 66408 MouseEntrez Gene 259271 RatEntrez Gene 54840 Human
  UniProt ID Q7Z2E3
• Background: This gene encodes a member of the histidine triad (HIT) superfamily. The encoded protein may play a role in single-stranded DNA repair through its nucleotide-binding activity and its diadenosine polyphosphate hydrolase activity. Mutations in this gene have been associated with ataxia-ocular apraxia. Alternatively spliced transcript variants have been identified for this gene.
• Synonyms: AOA; AOA1; AXA1; EAOH; EOAHA; FHA-HIT

Reference Data

• Protein Families: Druggable Genome