SAE1 Rabbit Polyclonal Antibody

CAT#: TA349544

Rabbit Polyclonal Anti-SAE1 Antibody

Product Images

Gel: 15%SDS-PAGE Lysate: 40 μg Lane 1-2: 293T cells A431 cells Primary antibody: TA349544 (SAE1 Antibody) at dilution 1/250 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 second

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA349544 (SAE1 Antibody) at dilution 1/20 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA349544 (SAE1 Antibody) at dilution 1/20, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA349544 (SAE1 Antibody) at dilution 1/20 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using TA349544 (SAE1 Antibody) at dilution 1/20, treated with fusion protein. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: 293T and A431 cells
  IHC: 25-100
  Positive control: Human thyroid cancer
  Predicted cell location: Nucleus
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human SAE1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 38 kDa
• Gene Name: SUMO1 activating enzyme subunit 1
• Database Link:
  NP_005491
  Entrez Gene 56459 MouseEntrez Gene 308384 RatEntrez Gene 10055 Human
  UniProt ID Q9UBE0
• Background: Posttranslational modification of proteins by the addition of the small protein SUMO, or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins.
• Synonyms: AOS1; HSPC140; SUA1; UBLE1A

Reference Data

• Protein Pathways: Ubiquitin mediated proteolysis