Hsp40 (DNAJB1) Rabbit Polyclonal Antibody

CAT#: TA349546

Rabbit Polyclonal Anti-DNAJB1 Antibody

Product Images

Gel: 15%SDS-PAGE Lysate: 40 μg Lane: 293T cells Primary antibody: TA349546 (DNAJB1 Antibody) at dilution 1/750 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 second

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  Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TA349546 (DNAJB1 Antibody) at dilution 1/40 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TA349546 (DNAJB1 Antibody) at dilution 1/40, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using TA349546 (DNAJB1 Antibody) at dilution 1/40 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using TA349546 (DNAJB1 Antibody) at dilution 1/40, treated with fusion protein. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: 293T cells
  IHC: 50-200
  Positive control: Human lung cancer
  Predicted cell location: Cytoplasm and Nucleus
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human DNAJB1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 38 kDa
• Gene Name: DnaJ heat shock protein family (Hsp40) member B1
• Database Link:
  NP_006136
  Entrez Gene 81489 MouseEntrez Gene 3337 Human
  UniProt ID P25685
• Background: Heat shock protein 40 (HSP 40) family proteins bind to HSP 70 through their J-domain and regulate the function of HSP 70 by stimulating HSP 70 ATPase activity. HSP 40, also known as DnaJ, functions together with DnaK (HSP 70) and GrpE as a molecular chaperone, involving them in assembly and disassembly of protein complexes, protein folding, renaturation of denatured proteins, prevention of protein aggregation and protein export. HSP 40 stimulates the association between HSC 70 and HIP and translocates rapidly from the cytoplasm to the nuclei, and especially to the nucleoli, upon heat shock. There are five known HSP 40 family proteins.
• Synonyms: Hdj1; Hsp40; HSPF1; RSPH16B; Sis1