TLR8 Rabbit Polyclonal Antibody

CAT#: TA349553

Rabbit Polyclonal Anti-TLR8 Antibody


USD 345.00

In Stock*

Size
    • 100 ul

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Specifications

Product Data
Applications ELISA, IHC
Recommended Dilution IHC: 50-200
Positive control: Human thyroid cancer
Predicted cell location: Cytoplasm
Reactivities Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein of human TLR8
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name toll like receptor 8
Background The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.
Synonyms CD288
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Toll-like receptor signaling pathway

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