SPHK2 Rabbit Polyclonal Antibody

CAT#: TA349657

Rabbit Polyclonal Anti-SPHK2 Antibody


USD 345.00

In Stock*

Size
    • 100 ul

Other products for "SPHK2"

Specifications

Product Data
Applications IHC, WB
Recommended Dilution WB: 200-1000
WB positive control: Mouse liver tissue
IHC: 100-300
Positive control: Human colon cancer
Predicted cell location: Cytoplasm and membrane
Reactivities Human, Mouse
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein of human SPHK2
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 69 kDa
Gene Name sphingosine kinase 2
Background This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Synonyms SK-2; SK 2; SPK-2; SPK 2
Reference Data
Protein Families Druggable Genome
Protein Pathways Calcium signaling pathway, Fc gamma R-mediated phagocytosis, Metabolic pathways, Sphingolipid metabolism, VEGF signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.