CARD11 Rabbit Polyclonal Antibody

CAT#: TA349744

Rabbit Polyclonal Anti-CARD11 Antibody


USD 345.00

In Stock*

Size
    • 100 ul

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Specifications

Product Data
Applications IHC
Recommended Dilution IHC: 50-200
Positive control: Human liver cancer
Predicted cell location: Cytoplasm or Nucleus
Reactivities Human, Mouse
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein of human CARD11
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name caspase recruitment domain family member 11
Background The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation.
Synonyms BENTA; BIMP3; CARMA1; IMD11; PPBL
Reference Data
Protein Families Druggable Genome
Protein Pathways B cell receptor signaling pathway, T cell receptor signaling pathway

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