IL2 Receptor beta (IL2RB) Rabbit Polyclonal Antibody

CAT#: TA349756

Rabbit Polyclonal Anti-IL2RB Antibody


USD 345.00

In Stock*

Size
    • 100 ul

Product Images

Other products for "IL2RB"

Specifications

Product Data
Applications IHC, WB
Recommended Dilution WB: 500-2000
WB positive control: HepG2, 231, Raji, 293T cell lysates
IHC: 50-200
Positive control: Human liver cancer
Predicted cell location: Cytoplasm
Reactivities Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein of human IL2RB
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 61 kDa
Gene Name interleukin 2 receptor subunit beta
Background The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein.
Synonyms CD122; IL15RB; P70-75
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cytokine-cytokine receptor interaction, Endocytosis, Jak-STAT signaling pathway

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.