CD46 Rabbit Polyclonal Antibody

CAT#: TA349781

Rabbit Polyclonal Anti-CD46 Antibody


USD 345.00

4 Weeks*

Size
    • 100 ul

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Specifications

Product Data
Applications IHC
Recommended Dilution IHC: 25-100
Positive control: Human colon cancer
Predicted cell location: Cytoplasm
Reactivities Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein of human CD46
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name CD46 molecule
Background The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization.
Synonyms AHUS2; MCP; MIC10; TLX; TRA2.10
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Complement and coagulation cascades

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.