DARPP32 (PPP1R1B) Rabbit Polyclonal Antibody

CAT#: TA349866

Rabbit Polyclonal Anti-PPP1R1B Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human colon cancer tissue using TA349866 (PPP1R1B Antibody) at dilution 1/50 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human colon cancer tissue using TA349866 (PPP1R1B Antibody) at dilution 1/50, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 50-200
  Positive control: Human colon cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human PPP1R1B
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: protein phosphatase 1 regulatory inhibitor subunit 1B
• Database Link:
  NP_115568
  Entrez Gene 360616 RatEntrez Gene 84152 Human
  UniProt ID Q9UD71
• Background: This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene
• Synonyms: DARPP-32; DARPP32

Reference Data

• Protein Families: Druggable Genome