DNA Ligase I (LIG1) Rabbit Polyclonal Antibody
Other products for "LIG1"
Specifications
Product Data | |
Applications | IHC |
Recommended Dilution | IHC: 100-300 Positive control: Human esophagus cancer Predicted cell location: Nucleus |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Fusion protein of human LIG1 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | DNA ligase 1 |
Database Link | |
Background | This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants. |
Synonyms | MGC117397; MGC130025 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Base excision repair, DNA replication, Mismatch repair, Nucleotide excision repair |
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.