EEF2K Rabbit Polyclonal Antibody

CAT#: TA349921

Rabbit Polyclonal Anti-EEF2K Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane 1-3: PC3 NIH/3T3 Jurkat cell lysates Primary antibody: TA349921 (EEF2K Antibody) at dilution 1/500 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 1 minute

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA349921 (EEF2K Antibody) at dilution 1/80 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA349921 (EEF2K Antibody) at dilution 1/80, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TA349921 (EEF2K Antibody) at dilution 1/80 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TA349921 (EEF2K Antibody) at dilution 1/80, treated with fusion protein. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: PC3, NIH/3T3, Jurkat cell lysates
  IHC: 50-200
  Positive control: Human liver cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human EEF2K
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 82 kDa
• Gene Name: eukaryotic elongation factor 2 kinase
• Database Link:
  NP_037434
  Entrez Gene 13631 MouseEntrez Gene 25435 RatEntrez Gene 29904 Human
  UniProt ID O00418
• Background: This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment.
• Synonyms: eEF-2K; HSU93850

Reference Data

• Protein Families: Druggable Genome, Protein Kinase