Emerin (EMD) Rabbit Polyclonal Antibody

CAT#: TA349933

Rabbit Polyclonal Anti-EMD Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane 1-2: 293T cells A549 cells Primary antibody: TA349933 (EMD Antibody) at dilution 1/1600 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 5 seconds

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1000-5000
  WB positive control: 293T and A549 cells
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human EMD
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 29 kDa
• Gene Name: emerin
• Database Link:
  NP_000108
  Entrez Gene 2010 Human
  UniProt ID P50402
• Background: Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family. It mediates membrane anchorage to the cytoskeleton. Dreifuss-Emery muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the emerin gene.
• Synonyms: EDMD; LEMD5; STA

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)