CD89 (FCAR) Rabbit Polyclonal Antibody

CAT#: TA349973

Rabbit Polyclonal Anti-FCAR Antibody

Product Images

Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane: Mouse brain tissue, Primary antibody: (FCAR Antibody) at dilution 1/700, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds

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  The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using (FCAR Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)

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  The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using (FCAR Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1000-2000, WB: 200-1000, IHC: 25-100
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human FCAR
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 32 kDa
• Gene Name: Fc fragment of IgA receptor
• Database Link:
  NP_579803
  Entrez Gene 2204 Human
  UniProt ID P24071
• Background: This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
• Synonyms: CD89; CTB-61M7.2; FcalphaRI

Reference Data

• Protein Families: Transmembrane