HIST4H4 Rabbit Polyclonal Antibody

CAT#: TA350047

Rabbit Polyclonal Anti-HIST4H4 Antibody

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: K562 cells, mouse pancreas tissue and Hela cells, mouse thymus tissue and 293T cells, NIH/3T3 and LoVo cells
  IHC: 50-200
  Positive control: Human colon cancer
  Predicted cell location: Nucleus
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human HIST4H4
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 11 kDa
• Gene Name: histone cluster 4, H4
• Database Link:
  NP_778224
  Entrez Gene 320332 MouseEntrez Gene 680097 RatEntrez Gene 121504 Human
  UniProt ID P62805
• Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element.
• Synonyms: H4; p

Reference Data

• Protein Pathways: Systemic lupus erythematosus