SETD7 Rabbit Polyclonal Antibody

CAT#: TA350048

Rabbit Polyclonal Anti-SETD7 Antibody


USD 345.00

In Stock*

Size
    • 100 ul

Product Images

Other products for "SETD7"

Specifications

Product Data
Applications IHC
Recommended Dilution IHC: 50-200
Positive control: Human tonsil
Predicted cell location: Nucleus and Cytoplasm
Reactivities Human, Mouse
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein of human SETD7
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name SET domain containing lysine methyltransferase 7
Background The methylation of histones plays a pivotal role in the regulation of chromatin structure and gene expression. Histone methylation can occur on Arg or Lys residues, with an exquisite site selectivity for Lys methylation at specific positions in the N-termini of histones H3 and H4. SET7/9, a histone methyltransferase (HMTase), which transfers methyl groups to Lys4 of histone H3, forms a complex with S-adenosyl-L-methionine. This complex contains an active site consisting of a binding pocket where an AdoMet molecule in an unusual conformation binds, a narrow substrate-specific channel that only unmethylated lysine residues can access and a catalytic tyrosine residue.
Synonyms 9; KMT7; SET7; SET9
Reference Data
Protein Families Druggable Genome
Protein Pathways Lysine degradation

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.