CD41 (ITGA2B) Rabbit Polyclonal Antibody

CAT#: TA350095

Rabbit Polyclonal Anti-ITGA2B Antibody


USD 345.00

In Stock*

Size
    • 100 ul

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Other products for "ITGA2B"

Specifications

Product Data
Applications IHC, WB
Recommended Dilution WB: 200-1000
WB positive control: Human fetal liver and placenta tissue
IHC: 50-200
Positive control: Human colon cancer
Predicted cell location: Cytoplasm
Reactivities Human, Mouse
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein of human ITGA2B
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 113 kDa
Gene Name integrin subunit alpha 2b
Background ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
Synonyms BDPLT2; BDPLT16; CD41; CD41B; GP2B; GPIIb; GT; GTA; HPA3; PPP1R93
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Hypertrophic cardiomyopathy (HCM), Pathways in cancer, Regulation of actin cytoskeleton, Small cell lung cancer

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