Lysyl tRNA synthetase (KARS) Rabbit Polyclonal Antibody

CAT#: TA350109

Rabbit Polyclonal Anti-KARS Antibody

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: K562, A549, HT-29, 293T, Hela and Jurkat cells
  IHC: 100-300
  Positive control: Human brain
  Predicted cell location: Cytoplasm or Nucleus
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human KARS
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 68 kDa
• Gene Name: lysyl-tRNA synthetase
• Database Link:
  NP_005539
  Entrez Gene 85305 MouseEntrez Gene 292028 RatEntrez Gene 3735 Human
  UniProt ID Q15046
• Background: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Synonyms: CMTRIB; DFNB89; KARS1; KARS2; KRS

Reference Data

• Protein Pathways: Aminoacyl-tRNA biosynthesis