NDUFA1 Rabbit Polyclonal Antibody

CAT#: TA350206

Rabbit Polyclonal Anti-NDUFA1 Antibody

Product Images

Gel: 12%SDS-PAGE Lysate: 40 μg Lane 1-4: 293T cell Mouse brain tissue Mouse heart tissue Rat skeletal muscle tissue lysates Primary antibody: TA350206 (NDUFA1 Antibody) at dilution 1/800 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 40 seconds

• 

  Immunohistochemistry of paraffin-embedded Human breast cancer tissue using TA350206 (NDUFA1 Antibody) at dilution 1/100 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human breast cancer tissue using TA350206 (NDUFA1 Antibody) at dilution 1/100, treated with fusion protein. (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using TA350206 (NDUFA1 Antibody) at dilution 1/100 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using TA350206 (NDUFA1 Antibody) at dilution 1/100, treated with fusion protein. (Original magnification: ×200)

Show all 5 images

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: 293T cell, Mouse brain tissue, Mouse heart tissue, Rat skeletal muscle tissue lysates
  IHC: 100-300
  Positive control: Human breast cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human NDUFA1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 8 kDa
• Gene Name: NADH:ubiquinone oxidoreductase subunit A1
• Database Link:
  NP_004532
  Entrez Gene 4694 Human
  UniProt ID O15239
• Background: The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane.
• Synonyms: CI-MWFE; MWFE; ZNF183

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Alzheimer's disease, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease