RAD17 Rabbit Polyclonal Antibody

CAT#: TA350323

Rabbit Polyclonal Anti-RAD17 Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Lovo cells
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human RAD17
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 77 kDa
• Gene Name: RAD17 checkpoint clamp loader component
• Database Link:
  NP_579922
  Entrez Gene 19356 MouseEntrez Gene 5884 Human
  UniProt ID O75943
• Background: The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage.
• Synonyms: CCYC; HRAD17; R24L; RAD17SP; RAD24

Reference Data

• Protein Families: Druggable Genome