RBM5 Rabbit Polyclonal Antibody

CAT#: TA350337

Rabbit Polyclonal Anti-RBM5 Antibody

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Huvec, hepg2, 293T and A549 cells
  IHC: 25-100
  Positive control: Human prostate cancer
  Predicted cell location: Nucleus and Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human RBM5
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 92 kDa
• Gene Name: RNA binding motif protein 5
• Database Link:
  NP_005769
  Entrez Gene 83486 MouseEntrez Gene 300996 RatEntrez Gene 10181 Human
  UniProt ID P52756
• Background: This gene is a candidate tumor suppressor gene which encodes a nuclear RNA binding protein that is a component of the spliceosome A complex. The encoded protein plays a role in the induction of cell cycle arrest and apoptosis through pre-mRNA splicing of multiple target genes including the tumor suppressor protein p53. This gene is located within the tumor suppressor region 3p21.3, and may play a role in the inhibition of tumor transformation and progression of several malignancies including lung cancer.
• Synonyms: G15; H37; LUCA15; RMB5

Reference Data

• Protein Families: Druggable Genome