RNF20 Rabbit Polyclonal Antibody

CAT#: TA350359

Rabbit Polyclonal Anti-RNF20 Antibody


USD 345.00

In Stock*

Size
    • 100 ul

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Specifications

Product Data
Applications IHC, WB
Recommended Dilution WB: 1000-5000
WB positive control: Lovo, A172, A375, 231, Jurkat and hela cells
IHC: 20-100
Positive control: Human esophagus cancer
Predicted cell location: Nucleus
Reactivities Human, Mouse
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein of human RNF20
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 114 kDa
Gene Name ring finger protein 20
Background The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor.
Synonyms BRE1; BRE1A; hBRE1
Reference Data
Protein Families Druggable Genome

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