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RNF20 Rabbit Polyclonal Antibody
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Other products for "RNF20"
Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommended Dilution | WB: 1000-5000 WB positive control: Lovo, A172, A375, 231, Jurkat and hela cells IHC: 20-100 Positive control: Human esophagus cancer Predicted cell location: Nucleus |
| Reactivities | Human, Mouse |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human RNF20 |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Predicted Protein Size | 114 kDa |
| Gene Name | ring finger protein 20 |
| Database Link | |
| Background | The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. |
| Synonyms | BRE1; BRE1A; hBRE1 |
| Reference Data | |
| Protein Families | Druggable Genome |
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.