TRIM21 Rabbit Polyclonal Antibody

CAT#: TA350446

Rabbit Polyclonal Anti-TRIM21 Antibody


USD 345.00

In Stock*

Size
    • 100 ul

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Specifications

Product Data
Applications IHC
Recommended Dilution IHC: 25-100
Positive control: Human ovarian cancer
Predicted cell location: Cytoplasm and Cell membrane
Reactivities Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein of human TRIM21
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name tripartite motif containing 21
Background This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus.
Synonyms RNF81; Ro; RO52; SSA; SSA1
Reference Data
Protein Families Druggable Genome
Protein Pathways Systemic lupus erythematosus

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