TRIM21 Rabbit Polyclonal Antibody

CAT#: TA350447

Rabbit Polyclonal Anti-TRIM21 rabbit polyclonal antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane 1-3: Lovo cells A549 cells hela cells Primary antibody: TA350447 (TRIM21 Antibody) at dilution 1/400 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 10 seconds

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1000-5000
  WB positive control: Lovo, A549 and hela cells
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human TRIM21
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 54 kDa
• Gene Name: tripartite motif containing 21
• Database Link:
  NP_003132
  Entrez Gene 6737 Human
  UniProt ID P19474
• Background: This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus.
• Synonyms: RNF81; Ro; RO52; SSA; SSA1

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Systemic lupus erythematosus