TLK2 Rabbit Polyclonal Antibody

CAT#: TA350512

Rabbit Polyclonal Anti-TLK2 Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane 1-5: 293T HT-29 RAW264.7 LOVO TM4 cell lysates Primary antibody: TA350512 (TLK2 Antibody) at dilution 1/650 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 10 seconds

• 

  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA350512 (TLK2 Antibody) at dilution 1/120 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA350512 (TLK2 Antibody) at dilution 1/120, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: 293T, HT-29, RAW264.7, LOVO, TM4 cell lysates
  IHC: 50-200
  Positive control: Human liver cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human TLK2
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: tousled like kinase 2
• Database Link:
  NP_006843
  Entrez Gene 24086 MouseEntrez Gene 11011 Human
  UniProt ID Q86UE8
• Background: This gene encodes a nuclear serine/threonine kinase that was first identified in Arabidopsis. The encoded protein is thought to function in the regulation of chromatin assembly in the S phase of the cell cycle by regulating the levels of a histone H3/H4 chaperone. This protein is associated with double-strand break repair of DNA damage caused by radiation. Pseudogenes of this gene are present on chromosomes 10 and 17. Alternate splicing results in multiple transcript variants.
• Synonyms: HsHPK; PKU-ALPHA

Reference Data

• Protein Families: Druggable Genome, Protein Kinase