TWIST2 Rabbit Polyclonal Antibody

CAT#: TA350555

Rabbit Polyclonal Anti-TWIST2 Antibody

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 25-100
  Positive control: Human liver cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Full length of human TWIST2
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: twist family bHLH transcription factor 2
• Database Link:
  NP_476527
  Entrez Gene 13345 MouseEntrez Gene 59327 RatEntrez Gene 117581 Human
  UniProt ID Q8WVJ9
• Background: The protein encoded by this gene is a basic helix-loop-helix type transcription factor and shares similarity with Twist. This protein may inhibit osteoblast maturation and maintain cells in a preosteoblast phenotype during osteoblast development. This gene may be upregulated in certain cancers. Mutations in this gene cause focal facial dermal dysplasia 3, Setleis type. Two transcript variants encoding the same protein have been found.
• Synonyms: AMS; BBRSAY; bHLHa39; DERMO1; FFDD3; SETLSS

Reference Data

• Protein Families: Druggable Genome, Transcription Factors