RAB17 Rabbit Polyclonal Antibody

CAT#: TA350622

Rabbit Polyclonal Anti-RAB17 Antibody

Product Images

Gel: 12%SDS-PAGE Lysate: 40 μg Lane: TM4 cells Primary antibody: TA350622 (RAB17 Antibody) at dilution 1/200 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 20 seconds

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  Immunohistochemistry of paraffin-embedded Human breast cancer tissue using TA350622 (RAB17 Antibody) at dilution 1/40 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human breast cancer tissue using TA350622 (RAB17 Antibody) at dilution 1/40, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: TM4 cells
  IHC: 30-150
  Positive control: Human breast cancer
  Predicted cell location: Cell membrane
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human RAB17
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 23 kDa
• Gene Name: RAB17, member RAS oncogene family
• Database Link:
  NP_071894
  Entrez Gene 19329 MouseEntrez Gene 64284 Human
  UniProt ID Q9H0T7
• Background: The Rab subfamily of small GTPases plays an important role in the regulation of membrane trafficking. RAB17 is an epithelial cell-specific GTPase. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion.
• Synonyms: FLJ12538

Reference Data

• Protein Families: Druggable Genome