HCN4 Rabbit Polyclonal Antibody

CAT#: TA350689

Rabbit Polyclonal Anti-HCN4 Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TA350689 (HCN4 Antibody) at dilution 1/35 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TA350689 (HCN4 Antibody) at dilution 1/35, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 25-100
  Positive control: Human esophagus cancer
  Predicted cell location: Cell membrane
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human HCN4
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: hyperpolarization activated cyclic nucleotide gated potassium channel 4
• Database Link:
  NP_005468
  Entrez Gene 59266 RatEntrez Gene 330953 MouseEntrez Gene 10021 Human
  UniProt ID Q9Y3Q4
• Background: This gene encodes a member of the hyperpolarization-activated cyclic nucleotide-gated potassium channels. The encoded protein shows slow kinetics of activation and inactivation, and is necessary for the cardiac pacemaking process. This channel may also mediate responses to sour stimuli. Mutations in this gene have been linked to sick sinus syndrome 2, also known as atrial fibrillation with bradyarrhythmia or familial sinus bradycardia. Two pseudogenes have been identified on chromosome 15.
• Synonyms: SSS2

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Cyclic nucleotide gated, Transmembrane