ING1 Rabbit Polyclonal Antibody

CAT#: TA350698

Rabbit Polyclonal Anti-ING1 Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Hela cells and mouse brain tissue, Jurkat and Raw264.7 cells
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human ING1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 47 kDa
• Gene Name: inhibitor of growth family member 1
• Database Link:
  NP_937861
  Entrez Gene 26356 MouseEntrez Gene 3621 Human
  UniProt ID Q9UK53
• Background: This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.
• Synonyms: p24ING1c; p33; p33ING1; p33ING1b; p47; p47ING1a

Reference Data

• Protein Families: Druggable Genome, Transcription Factors