CD163 Rabbit Polyclonal Antibody
Other products for "CD163"
Specifications
Product Data | |
Applications | IHC |
Recommended Dilution | IHC: 25-100 Positive control: Human gasrtic cancer Predicted cell location: secreted |
Reactivities | Human |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human CD163 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | CD163 molecule |
Database Link | |
Background | The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
Synonyms | M130; MM130; SCARI1 |
Reference Data | |
Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.