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PI 3 Kinase Class 3 (PIK3C3) Rabbit Polyclonal Antibody
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Other products for "PIK3C3"
Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommended Dilution | IHC: 20-100 Positive control: Human brain Predicted cell location: Cytoplasm and Cell membrane |
| Reactivities | Human, Mouse, Rat |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human PIK3C3 |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Gene Name | phosphatidylinositol 3-kinase catalytic subunit type 3 |
| Database Link | |
| Background | Phosphatidylinositol 3-kinase catalytic subunit type 3 is an enzyme that in humans is encoded by thePIK3C3 gene. PI3KC3 is a catalytic subunit of the PI3K complex involved in the transport of lysosomal enzyme precursors to lysosomes. This enzyme acts catalytically to convert 1-phosphatidyl-1D-myo-inositol to 1-phosphatidyl-1D-myo-inositol 3-phosphate Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. |
| Synonyms | hVps34; VPS34; Vps34 |
| Reference Data | |
| Protein Families | Druggable Genome |
| Protein Pathways | Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system, Regulation of autophagy |
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