Klotho (KL) Rabbit Polyclonal Antibody

CAT#: TA350910

Rabbit Polyclonal Anti-KL Antibody

Product Images

Gel: 6%SDS-PAGE Lysate: 40 μg Lane: Mouse placenta tissue lysate Primary antibody: TA350910 (KL Antibody) at dilution 1/400 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 2 minutes

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC: 50-300
  Positive control: Human colorectal cancer
  Predicted cell location: Nucleus
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human KL
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 62 kDa
• Gene Name: klotho
• Database Link:
  NP_004786
  Entrez Gene 16591 MouseEntrez Gene 83504 RatEntrez Gene 9365 Human
  UniProt ID Q9UEF7
• Background: This gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss.
• Synonyms: klotho; OTTHUMP00000018796

Reference Data

• Protein Families: Secreted Protein, Transmembrane