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SPR Rabbit Polyclonal Antibody
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Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommended Dilution | WB: 500-2000 WB positive control: Human chromaffin cells tumor tissue and lovo cells IHC: 50-200 Positive control: Human breast cancer Predicted cell location: Cytoplasm |
| Reactivities | Human |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human SPR |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Predicted Protein Size | 28 kDa |
| Gene Name | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
| Database Link | |
| Background | This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1. |
| Synonyms | SDR38C1 |
| Reference Data | |
| Protein Families | Druggable Genome |
| Protein Pathways | Folate biosynthesis, Metabolic pathways |
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.