Adrenomedullin (ADM) Rabbit Polyclonal Antibody

CAT#: TA350960

Rabbit Polyclonal Anti-ADM Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using TA350960 (ADM Antibody) at dilution 1/20 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using TA350960 (ADM Antibody) at dilution 1/20, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Human left kidney tissue
  IHC: 25-100
  Positive control: Human thyroid cancer
  Predicted cell location: cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human ADM
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: adrenomedullin
• Database Link:
  NP_001115
  Entrez Gene 11535 MouseEntrez Gene 25026 RatEntrez Gene 133 Human
  UniProt ID P35318
• Background: Adrenomedullin, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor, called preproadrenomedullin, is 185 amino acids long. By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues. Genomic ADM DNA consists of 4 exons and 3 introns, with the 5-prime flanking region containing TATA, CAAT, and GC boxes. There are also multiple binding sites for activator protein-2 and a cAMP-regulated enhancer element.
• Synonyms: AM; PAMP

Reference Data

• Protein Families: Druggable Genome, Secreted Protein