CACNA1G Rabbit Polyclonal Antibody

CAT#: TA351023

Rabbit Polyclonal Anti-CACNA1G Antibody


USD 345.00

In Stock*

Size
    • 100 ul

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Specifications

Product Data
Applications IHC
Recommended Dilution IHC: 15-50
Positive control: Human thyroid cancer
Predicted cell location: Cytoplasm
Reactivities Human, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide of human CACNA1G
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name calcium voltage-gated channel subunit alpha1 G
Background Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas, the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1A subunit, which is predominantly expressed in neuronal tissue. Mutations in this gene are associated with 2 neurologic disorders, familial hemiplegic migraine and episodic ataxia 2.
Synonyms Ca(V)T.1; Cav3.1; NBR13
Reference Data
Protein Families Druggable Genome, Ion Channels: Calcium, Transmembrane
Protein Pathways Calcium signaling pathway, MAPK signaling pathway, Type II diabetes mellitus

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