CD30 (TNFRSF8) Rabbit Polyclonal Antibody

CAT#: TA351043

Rabbit Polyclonal Anti-TNFRSF8 Antibody


USD 345.00

In Stock*

Size
    • 100 ul

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Specifications

Product Data
Applications IHC
Recommended Dilution IHC: 100-300
Positive control: Human thyroid cancer
Predicted cell location: Cytoplasm
Reactivities Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide of human TNFRSF8
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name tumor necrosis factor receptor superfamily member 8
Background The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Synonyms CD30; D1S166E; Ki-1
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Stem cell - Pluripotency, Transmembrane
Protein Pathways Cytokine-cytokine receptor interaction

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