SIGLEC6 Rabbit Polyclonal Antibody

CAT#: TA351047

Rabbit Polyclonal Anti-SIGLEC6 Antibody

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: A549 cell lysate
  IHC: 50-300
  Positive control: Human liver cancer
  Predicted cell location: Secreted and Cell membrane
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human SIGLEC6
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 50 kDa
• Gene Name: sialic acid binding Ig like lectin 6
• Database Link:
  NP_942142
  Entrez Gene 946 Human
  UniProt ID O43699
• Background: The SIGLEC6 gene to 19q13.3, which is where the CD33 gene is located. Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. Expressed at high levels in placenta (cyto- and syncytiotrophoblastic cells) and at lower levels in spleen, peripheral blood leukocytes (predominantly B-cells) and small intestine.
• Synonyms: CD33L; CD33L1; CD33L2; CD327; CDW327; OBBP1

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane