CD47 Rabbit Polyclonal Antibody

CAT#: TA351054

Rabbit Polyclonal Anti-CD47 Antibody

Product Images

Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane 1-2: SKOV3 cells, Hela cells, Primary antibody: (CD47 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds

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  The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using (CD47 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)

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  The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using (CD47 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1000-5000, WB: 200-1000, IHC: 50-200
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human CD47
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 35 kDa
• Gene Name: CD47 molecule
• Database Link:
  NP_942088
  Entrez Gene 961 Human
  UniProt ID Q08722
• Background: This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Alternatively spliced transcript variants have been found for this gene.
• Synonyms: IAP; MER6; OA3

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: ECM-receptor interaction