CEBP Beta (CEBPB) Rabbit Polyclonal Antibody

CAT#: TA351070

Rabbit Polyclonal Anti-CEBPB Antibody

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 50-200
  Positive control: Human thyroid cancer
  Predicted cell location: Nucleus and Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human CEBPB
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: CCAAT/enhancer binding protein beta
• Database Link:
  NP_005185
  Entrez Gene 12608 MouseEntrez Gene 24253 RatEntrez Gene 1051 Human
  UniProt ID P17676
• Background: The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.
• Synonyms: C; EBP-beta; IL6DBP; NF-IL6; TCF5

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transcription Factors