DMT1 (SLC11A2) Rabbit Polyclonal Antibody

CAT#: TA351143

Rabbit Polyclonal Anti-SLC11A2 Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TA351143 (SLC11A2 Antibody) at dilution 1/65 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TA351143 (SLC11A2 Antibody) at dilution 1/65, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Raji cells and human fetal liver tissue, NIH/3T3 cells and mouse brain tissue, hela cells
  IHC: 50-200
  Positive control: Human thyroid cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human SLC11A2
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: solute carrier family 11 member 2
• Database Link:
  NP_000608
  Entrez Gene 25715 RatEntrez Gene 4891 Human
  UniProt ID P49281
• Background: This gene encodes a member of the solute carrier family 11 protein family. The product of this gene transports divalent metals and is involved in iron absorption. Mutations in this gene are associated with hypochromic microcytic anemia with iron overload. A related solute carrier family 11 protein gene is located on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene.
• Synonyms: DCT1; DMT1; NRAMP2

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Lysosome